Dr. Mélanie Auffan

Surface reactivity, Ecotoxicity, and Genotoxicity
of Engineered Nanomaterials during their life cycle 
Address: CEREGE, Europole de l'Arbois BP80,
13545 Aix-en-Provence, FRANCE Cedex 4
Phone: +33 (0)4 42 97 15 43
Fax: +33 (0)4 42 97 15 59
auffan@cerege.fr

site duke

CEREGE: UMR 7330 CNRS/Aix-Marseille univ.
GDRi-iCEINT: international Consortium for the Environmental Implications of NanoTechnology
CEINT: Center for the Environmental Implications of NanoTechnology (USA)

 

ACADEMIC and PROFESSIONAL EXPERIENCES


Since 2009: CNRS research scientist, Aix en Provence, France 

Since 2013: Adjunct Assistant Professor, Civil and Environmental Engineering Department, Duke University, NC-USA

2007-2009: Research Associate, Civil and Environmental Engineering Department, Duke University, NC-USA

2004-2007: PhD in Geosciences of the Environment - Aix Marseille University 

2002-2004: Master's degree in Geosciences - Aix Marseille University  

2000-2002: Licence’s degree in Earth Science - Aix Marseille University


ARTICLES


2014

43. Fisichella, M. et al., Toxicity evaluation of manufactured CeO2 nanoparticles before and after alteration: combined physicochemical and whole-genome expression analysis in Caco-2 Cells. BMC Genomics; 15: 700, 2014.

42. Secret, E. et al., Two-photon excitation of porphyrin-functionalized porous silicon nanoparticles for photodynamic therapy. Advanced Materials; online, 2014.

41. Tella, M. et al., Transfer, transformation and impacts of ceria nanomaterials in aquatic mesocosms simulating a pond ecosystem. Environmental Science & Technology; 48, 9004-9013, 2014

40. Santaella, C. et al., TiO2-based nanocomposite used in sunscreens produces singlet oxygen under long-wave UV and sensitizes Escherichia coli to cadmium. Environmental Science & Technology 48, 5245-5253, 2014.

39. Barton, L. et al., Theory and methodology for determining nanoparticle affinity for heteroaggregation in environmental matrices using batch measurements. Environmental Engineering Science; 31, 1-7, 2014.

38. Barton, L. et al., Transformation of pristine and citrate-functionalized CeO2 nanoparticles in a laboratory-scale activated sludge reactor. Environmental Science & Technology; 48, 7289-7296, 2014.

37. Auffan et al., An adaptable mesocosm platform for performing integrated assessments of nanomaterial risk in complex environmental systems. Scientific reports; 4, 5608, 2014.

36. Auffan et al., Long-term aging of a CeO2 based nanocomposite used for wood protection. Environmental Pollution; 188, 1-7, 2014.

35. Auffan et al., Salinity-dependent silver nanoparticle uptake and transformation in Atlantic Killifish (Fundulus heteroclitus) embryos, Nanotoxicology; 8, 167-176, 2014

2013

34. Courbiere et al., Ultrastructural Interactions and Genotoxicity Assay of Cerium Dioxide nanoparticles on Mouse Oocytes, International Journal of Molecular Sciences; 14, 21613-21628, 2013.

33. Artells et al., Exposure to Cerium Dioxide Nanoparticles Differently Affect Swimming Performance And Survival In Two Daphnid Species, PlosOne; 8, e71260, 2013

32. Leveques et al., Assessing ecotoxicity and uptake of metals and metalloids in relation to two different earthworm species (Eiseina hortensis and Lumbricus terrestris), Environmental pollution; 179, 232-241, 2013

31. Auffan et al., Role of molting on the biodistribution of CeO2 nanoparticles within Daphnia pulex, Water Research; 47, 3921-3930, 2013

30. Liu et al., Protein corona formation for nanomaterials and proteins of a similar size: hard or soft corona, Nanoscale; 5, 1658-1668, 2013

2012

29. Liu et al., Influence of the length of Imogolite-Like nanotubes on their cytotoxicity and genotoxicity toward human dermal cells, Chemical Research in Toxicology; 25(11), 2513-2522, 2012

28. Auffan et al., Is there a Trojan horse effect during magnetic nanoparticles and metalloid co-contamination of human dermal fibroblasts?, Environmental Sciences & Technology; 46(19), 10789–10796 , 2012

27. Yang et al., Mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans, Environmental Sciences & Technology, 46(2), 1119–1127, 2012

26. Fisichella et al., Intestinal toxicity evaluation of TiO2 degraded surface-treated nanoparticles: a combined physico-chemical and toxicogenomics approach in caco-2 cells, Particles Fibers and Toxicology, 9(1); 18, 2012

25. Colman et al., Antimicrobial effects of commercial silver nanoparticles are attenuated in natural streamwater and sediment, Ecotoxicology, 21(7), 1867-1877, 2012

24. Kwok et al., Uptake of silvernanoparticles and toxicity to earlylifestages of Japanesemedaka (Oryzias latipes): Effect of coating materials, Aquatic Toxicology; 120-121; 59-66, 2012

23. Thill et al., Physico-chemical Control over the Single- or Double-Wall Structure of Aluminogermanate Imogolite-like Nanotubes, JACS;  134(8); 3780–3786, 2012

22. Thiery et al., Effects of metallic and metal oxide nanoparticles in aquatic and terrestrial food chains. Biomarkers responses in invertebrates and bacteria, International Journal of Nanotechnology; 9; 181-203, 2012

21. Masion et al., Environmental fate of nanoparticles: physical chemical and biological aspects – a few snapshot, International Journal of Nanotechnology; 9; 167-180, 2012

2011

20. Hull et al., Filter-feeding bivalves store and biodeposit colloidally stable gold nanoparticles, Environmental Sciences & Technology; 45(15); 6592–6599, 2011

19. Gondikas et al., Early-stage precipitation kinetics of zinc sulfide nanoclusters forming in the presence of cysteine, Chemical Geology; 329, 10-17, 2011

18. Yin et al., More than the Ions: The Effects of Silver Nanoparticles on Lolium multiflorum, Environmental Sciences & Technology; 45(6); 2360–2367, 2011

17. Charlet et al., Reactivity at (nano)particle-water interfaces, redox processes, and arsenic transport in the environment, C. R. Geosciences; 343; 123–139, 2011

16. Bottero et al., Manufactured metal and metal-oxide nanoparticles: Properties and perturbing mechanisms of their biological activity in ecosystems, C. R. Geosciences; 343; 168–176, 2011

15. Botta et al., TiO2-based nanoparticles released in water from commercialized sunscreens in a life-cycle perspective: Structures and quantities, Environmental Pollution; 159(6); 1543-1550, 2011

2010

14. Cotte et al., Environmental sciences at the ESRF, Synchrotron radiation news; 23(5), 2010

13. Meyer et al., Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans, Aquatic toxicology; 100(2); 140-50, 2010

12. Auffan et al., Inorganic manufactured nanoparticles: How their physico-chemical properties influence their biological effects in aqueous environments, Nanomedicine; 5(6); 999–1007, 2010

11. Auffan et al., Surface structural degradation of a TiO2-based nanomaterial used in cosmetics, Environmental Sciences & Technology; 44; 2689–2694, 2010

10. Labille et al., Aging of TiO2 nanocomposites used in sunscreen creams. Dispersion and fate of the byproducts in aqueous environment, Environmental Pollution; 158(12); 3482-3489, 2010

2009

9. Zeyons et al., Direct and indirect CeO2 nanoparticles toxicity for E.coli and SynechocystisNanotoxicology; 3(4); 284-295, 2009

8. Auffan et al., Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective, Nature Nanotechnology; 3(4); 634-641, 2009

7. Kovochich et al., Comparative toxicity of C60 aggregates towards mammalian cells: role of the tetrahydrofuran (THF) decompositionEnvironmental Sciences & Technology; 43(16); 6378–6384, 2009

6. Auffan et al., CeO2 nanoparticles induce DNA damage towards human dermal fibroblasts in vitro, Nanotoxicology; 3(2); 161-171; 2009

5. Auffan et al., Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro, Environmental Pollution; 157; 1127-1133; 2009

2008

4. Auffan et al., Relation between the redox state of iron-based nanoparticles and their cytotoxicity towards Escherichia Coli, Environmental Sciences & Technology; 42(17); 6730–6735, 2008

2. Thill et al., Cytotoxicity of CeO2 Nanoparticles for Escherichia coli. Physico-Chemical Insight of the Cytotoxicity, Environmental Sciences & Technology; 40(14); 6151-6156, 2006



BOOK CHAPTERS

7.Auffan M et al., Impacts and Physico-Chemical Behavior of Inorganic Nanoparticles in the Environment. In Nanomaterials: A Danger or a Promise?, Brayner R, Fievet F, Coradin T, Springer, 2012

6. Auffan et al., Ecotoxicity of Inorganic Nanoparticles: From Unicellular Organisms to Invertebrates. In Encyclopedia of Nanotechnology, Bhushan B, Springer, 2012

5. Auffan et al., Surface reactivity of manufactured nanoparticles, in Nanosciences - Tome 4 - Nanotoxicology and NanoethicsSpringer, 2011

4. Auffan et al., Ecotoxicology: reactivity toward living organisms, in Nanosciences - Tome 4 - Nanotoxicology and Nanoethics, Springer, 2011

3. Auffan et al., Reactivite de surface des nanoparticules, in Nanosciences - Tome 4 - Nanotoxicologie et Nanoethique, Belin, 2010

2. Auffan et al., Ecotoxicologie: reactivite vis-a-vis des organismes vivants, in Nanosciences - Tome 4 - Nanotoxicologie et Nanoethique, Belin, 2010

1. Auffan et al., Nanoparticles as adsorbant. In Environmental Nanotechnology, Wiesner M, Bottero JY, McGraw-Hill, 2007


AWARDS

'C'Nano interdisciplinarity 2009', French C'nano network

'2009 Outstanding Postdoc', Duke university (USA)

'Young researcher 2008', Europole Mediterraneen de l'Arbois

'Hauy-Lacroix 2008', French Society of Mineralogy and Crystallography