Appala Raju Badireddy

APPALA RAJU BADIREDDY, Ph.D.

Postdoctoral Research Associate

Department of Civil and Environmental Engineering

Center for the Environmental Implication of NanoTechnology (CEINT)

Duke University

121 Hudson Hall,

Durham, NC 27708, USA

Tel/Fax: 919-660-5518 (5351)/5219

Email: arb42@duke.edu


Education

  • Ph.D. Environmental Engineering, University of Houston, Houston, Texas
  • M.Tech. Chemical Engineering, Indian Institute of Technology, Madras, India
  • B.Tech. Chemical Engineering, Jawaharlal Nehru Technological University, Hyderabad, India

Professional Experience

  • 2009-Present: Research Associate, Duke University, Durham, NC
  • May-June 2012: Visiting Postdoctoral Research Associate, Centre Européen de Recherche et d’Enseignement des Géosciences de l’Environnement (CEREGE) in Aix-en-Provence, France
  • 2009-Present: Member of CEINT
  • 2003-2009: Research and Teaching Assistant, University of Houston, Houston, TX 2006-2008: Visiting Graduate Research Assistant, Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA (duration: Nov 2008, Nov-Jan 2007-08, May-July 2006)
  • 2001-2003: Research Assistant, Indian Institute of Technology, Madras, India

Awards

  • Gordon Research Conference on Environmental Nanotechnology, May 29-June 3, 2011: Travel award
  • Awarded the first prize in the Texas Water 2008 Water Environment Association of Texas student paper competition
  • Graduate Leadership Scholarship, Dept. Civil & Environmental Engineering, University of Houston, 2007-2008
  • Presidential Graduate Research Fellowship, University of Houston, 2003-2005

Research Highlights


Publications

  1. Badireddy, A.R., Marinakos, S.M., Chellam, S., and Wiesner, M.R.,"Lipophilic Nano-Bismuth Inhibits Bacterial Growth, Attachment, and Biofilm Formation", Surface Innovations (2013) 1 (SI3) p181-189
  2. Chae, S.R., Hotze, E.M., Badireddy, A.R., Lin, S., Kim, J.O., Wiesner, M.R.,"Environmental Implications and Applications of Carbon Nanomaterials in Water Treatment", Water Science and Technology (2013) 67 (11) p2582-2586
  3. Levard, C., Mitra, S., Yang, T., Jew, A.D., Badireddy, A.R., Lowry, G.V., Brown Jr, G.E.,"Effect of Chloride on the Dissolution Rate of Silver Nanoparticles and Toxicity to E. coli", Environmental Science and Technology (2013) 47 (11) p5738-5745.
  4. Wang, A., Marinakos, S.M., Badireddy, A.R., Powers, C.M., Houck, K.A., "Characterization of Physicochemical Properties of Nanomaterials and their Immediate Environments in High-Throughput Screening of Nanomaterial Biological Activity", WIREs Nanomedicine and Nanobiotechnology (2013) DOI: 10.1002/wnan.1229
  5. Arnold, M.C., Badireddy, A.R., Wiesner, M.R., Di Giulio, R.T., and Meyer, J.N., "Cerium Oxide, Nanoparticles are More Toxic than Equimolar Bulk Cerium Oxide in Caenorhabditis elegans", Archives of Environmental Contamination and Toxicology (2013) 1-10.
  6. Hendren, C.O., Badireddy, A.R., Casman, E., and Wiesner, M.R., "Modeling Nanomaterial Fate in Wastewater Treatment: Monte Carlo Simulation of Silver Nanoparticles (Nano-Ag)", Science of The Total Environment (2013), 449, p418-425.
  7. Badireddy, A.R., Wiesner, M.R., and Liu, J., "Detection, Characterization, and Abundance of Engineered Nanoparticles in Complex Waters by Hyperspectral Imagery With Enhanced Darkfield Microscopy," Environmental Science and Technology (2012), 46 (18), p10081-10088.
  8. Badireddy, A.R. *, Franer-Burdaz, J. *, Chellam, S., and Wiesner, M.R., " Bacteriophage Inactivation by UV-A Illuminated Fullerenes: Role of Nanoparticle-Virus Association and Biological Targets," Environmental Science and Technology, (2012) (*contributed equally), 46 (11), p5963-5970.
  9. Kwok, K.W.H., Auffan, M., Badireddy, A.R., Nelson, C.M., Wiesner, M.R., and Hinton, D.E., “Toxicity and Uptake of Silver Nanoparticles to Early Life Stages of Japanese Medaka (Oryzias Latipes): Effect of Coating Materials,” Aquatic Toxicology, (2012), 120, p59-66.
  10. Lowry, G.V., Espinasee, B., Badireddy, A.R., Reinsch, B., Bryant, L., Colman, B., Hsu-Kim, H., Matson, C., Richardson, C., and M.R. Wiesner, “Long-Term Transformation and Fate of Manufactured Ag NPs in a Simulated Large Scale Freshwater Emergent Wetland,” Environmental Science and Technology, (2012), 46 (13), p7027-7036.
  11. Powers, C.M., Slotkin, T.A.,Seidler, F.J., Badireddy, A.R., Padilla, S., “Silver Nanoparticles Alter Zebrafish Development and Larval Behavior: Distinct Roles for Particle size, Coating, and Composition”,  Neurotoxicology and Teratology, (2011), 33 (6) p708-714.
  12. Saathoff, J.G., Xia, X., Riviere, J.E., Inman, A.O., Badireddy, A.R., Wiesner, M.R., Monteiro-Riviere, N.A., “Evaluation of Toxicity and Inflammation in Three Different Hydroxylated Fullerenes (C60(OH)x) in Human Cells,” Toxicologist CD-An Official Journal of the Society of Toxicology, (2011), 1176, p.251.
  13. Badireddy, A.R., Chellam, S., “Bismuth Dimercaptopropanol (BisBAL) Inhibits Formation of Multispecies Wastewater Flocs”, Journal of Applied Microbiology, (2011), 110 (6), 1426-1437.
  14. Powers, C.M., Badireddy, A.R., Ryde, I.T., Seidler, F.J., Slotkin, T.A., “Silver Nanoparticles Compromise Neurodevelopment in PC12 Cells: Critical Contributions of Silver Ion, Particle size, Coating and Composition”, Environmental Health Perspectives, (2011), 119 (1), 37-44.
  15. Meyer, J.N., Lord, C.A., Yang, X.Y., Turner, E.A., Badireddy, A.R., Marinakos, S.M., Chilkoti, A., Wiesner, M.R., Auffan, M., “Intracellular Uptake and Associated Toxicity of Silver Nanoparticles in Caenorhabditis Elegans”, Aquatic Toxicology, (2010), 100, 140-150.
  16. Chae, S.R. *, Badireddy, A.R. *, Farner Budarz, J., Lin, S., Xiao, Y., Therezien, M., Wiesner, M.R., “Heterogenities in Fullerene Nanoparticle Aggregates Affecting Reactivity, Bioactivity, and Transport”, ACS Nano, (2010), 4 (9), 5011-5018 (*contributed equally).
  17. Badireddy, A.R., Chellam, S., Gassman, P.L., Engelhard, M.H., Lea, A.S., and Rosso, K.M., “Role of Extracellular Polymeric Substances in Bioflocculation of Activated Sludge Microorganisms under Glucose-controlled Conditions.” Water Research, (2010), 44 (15), 4505-4516.
  18. Hotze, E.M. *, Badireddy, A.R.*, Chellam, S., and Wiesner, M.R., “Mechanisms of Bacteriophage Inactivation via Singlet Oxygen Generation in UV Illuminated Fullerol Suspensions”, Environmental Science and Technology, (2009), 43(17), 6639-6645 (*contributed equally).
  19. Baltus, R., Badireddy, A.R., Xu, W., and Chellam, S., "Analysis of Configurational Effects on Hindered Convection of Nonspherical Bacteria and Viruses across Microfiltration Membranes," Industrial & Engineering Chemistry Research, (2009), 48, 2404–2413.
  20. Badireddy, A.R., Korpol, B.R., Chellam, S., Gassman, P.L., Engelhard, M.H., Lea, A.S., and K. M. Rosso, K.M., “Spectroscopic Characterization of Extracellular Polymeric Substances from Escherichia coli and Serratia marcescens: Suppression using Sub-Inhibitory Concentrations of Bismuth Thiols”,  Biomacromolecules, (2008), 9 (11), 3079–3089.
  21. Badireddy, A.R., Chellam, S., Yanina, S., Gassman, P.L., and Rosso, K.M., "Bismuth Dimercapto-propanol (BisBAL) Inhibits the Expression of Extracellular Polysaccharides and Proteins in Brevundimonas diminuta: Implications for Membrane Microfiltration," Biotechnology and Bioengineering, (2008), 99 (3), 634–643, (highlighted as cover art in the journal issue).
  22. Badireddy, A.R., E.M. Hotze, S. Chellam, P.J.J. Alvarez, and M.R. Wiesner, "Inactivation of Bacteriophages via Photosensitization of Fullerol Nanoparticles," Environmental Science and Technology, (2007), 41 (18), 662 –6632.

Presentations

  • Yang, X., Jiang, C., Hsu-Kim, H., Badireddy, A.R., Wiesner, M.R., Hinton, D.E., and Meyer, J.N., "In Vivo Study of the Role of Endocytosis in Silver Nanoparticle Uptake, Localization, and Toxicity in Caenorhabditis elegans, " Poster in Nanotechnology session, SETAC North America 33rd Annual Meeting, Nov 14, 2012, Long Beach, CA.
  • Yang, X., Jiang, C., Hsu-Kim, H., Badireddy, A.R., Wiesner, M.R., Hinton, D.E., and Meyer, J.N., "Behavior of Silver Nanoparticles and Interaction with Dissolved Organic Matter and Temperature in Caenorhabditis elegans," Poster in Nanotechnology session, SETAC North America 33rd Annual Meeting, Nov 14, 2012, Long Beach, CA.
  • Badireddy, A.R., Franer-Burdaz, J., Chellam, S., and Wiesner, M.R., " Bacteriophage Inactivation by UV-A Illuminated Fullerenes: Role of Nanoparticle-Virus Association and Biological Targets,” Poster in Environmental Sciences: Water, Gordon Research Conference, June 24-29, 2012, Holderness, NH.
  • Chellam, S., Badireddy, A.R., and Cogan, N., “Bacterial Deposition and Fouling During Dead-End Microfiltration”, North American Membrane Society Annual Meeting, Microorganism Interactions with Porous Membrane session, June 9-13, 2012, New Orleans, LA.
  • Badireddy, A.R. and Wiesner, M.R., “Detection and Analysis of Engineered Nanoparticles in Environmental Waters Using Hyperspectral Darkfield Microscopy,” Poster in Environmental Nanotechnology at Gordon Research Conference, May 29-June 3, 2011, Waterville Valley, NH.
  • Badireddy, A.R. and Wiesner, M.R., “Detection and Analysis of Engineered Nanoparticles in Environmental Waters Using Hyperspectral Dark-field Microscopy,” ICEIN, May 9-11, 2011, Durham, NC.
  • Badireddy, A.R., Soyer, E., and Wiesner, M.R., “Preparation and Characterization of Silver Nanoparticle Composite Ultrafiltration Membranes: Impact of Cleaning agents and Antibacterial Efficacy,” Membrane Technology Conference and Exposition, March 28-31, 2011, Long Beach CA.
  • Chellam, S., Badireddy, A.R., Hotze, E.M., and Wiesner. M.R., “Virus Inactivation is Mediated by Reactive Oxygen Species in Photosensitized Fullerol Nanoparticle Suspensions,” Session: Nanotechnology: Enabling Sustainable Solutions for Potable Water, Division of Environmental Chemistry, 239th ACS National Meeting & Exposition, March 21 – 25, 2010, San Francisco, CA.
  • Powers, C.M., Ryde, I.T., Badireddy, A.R., Seidler, F.J., and Slotkin, T.H., “Developmental Neurotoxicity of Silver Nanoparticles Modeled in PC12 Cells,” Society of Toxicology, March 7-11, 2010, Salt Lake City, Utah.
  • Baltus, R., Xu, W., Badireddy, A.R., and S. Chellam. “Rejection of Rod-Shaped Bacteria From Porous Membranes: Comparison of Experiment to Model Predictions,” Separations Division, AIChE Annual Meeting, November 8 – 13, 2009, Nashville, TN.
  • Badireddy, A.R., Chellam, S., Hotze, E.M., and Wiesner, M.R., "Virus Inactivation is Mediated by Reactive Oxygen Species in Photosensitized Fullerol Nanoparticle Suspensions," International Water Association conference on Particle Separations and Nanoparticles in Water, June 3 – 5, 2009, Durham, NC.
  • Badireddy, A.R., Hotze, E.M., Chellam, S., Alvarez, P.J.J., and Wiesner, M.R., "Inactivation of Bacteriophages via Photosensitization of Fullerol Nanoparticles," Poster in “Fresh Ideas” Session at AWWA Annual Conference and Exposition, June 8–12, 2008, Atlanta, GA.
  • Baltus, R., W. Xu, Badireddy, A.R., and Chellam, S., “Effect of Bacteria and Virus Shape on Rejection by Microfiltration Membranes: Comparison Of Experiment With Hindered Transport Theory,” Separations Division, AIChE Annual Meeting, November 4–9, 2007, Salt Lake City, UT.
  • Badireddy, A.R., Chellam, S., Yanina, S., Gassman, P.L., and Rosso, K.M., “Bismuth Dimercaptopropanol (BisBAL) Inhibits the Expression of Extracellular Polysaccharides and Proteins in Brevundimonas diminuta: Implications for Membrane Microfiltration”, North American Membrane Society, May 12 – 16, 2007.
  • Hotze, E.M., Badireddy, A.R., Wiesner, M.R., and Chellam, S., “Singlet Oxygen and Superoxide Production by Three Types of Aqueous Fullerene Suspensions”, 233rd ACS National Meeting, Chicago, IL, March 25 – 29, 2007.
  • Badireddy, A.R., Chellam, S., Yanina, S., Gassman, P.L., and Rosso, K.M., “Bismuth Dimercaptopropanol (BisBAL) Inhibits the Expression of Extracellular Polysaccharides and Proteins in Brevundimonas diminuta”, Student Paper for Texas Water 2007, WEAT and Texas Section AWWA Annual Conference April 10 – 13, Fort Worth, TX.
  • Badireddy, A.R. and Chellam, S., “Diffusivity Measurements of Bacteriophages by Gradient Diffusion and Dynamic Light Scattering”, Session #66; Colloidal & Interfacial Phenomena in Aquatic Systems in AIChE Annual Meeting, November 12 – 17, 2006. San Francisco, CA.
  • Badireddy, A.R. and Chellam, S., “Investigation of Virus Transport across Microfiltration membranes”, Student Paper for Texas Water 2005, WEAT and Texas Section AWWA Annual Conference April 5 – 8, 2005, Galveston, TX.